Computed tomagraphy image
Computerized medicine has become an invaluable complement to modern medicine. Current techniques for deriving body composition measures from medical images require tedious manual segmentation or segmentation by thresholding, the latter of which often produces errors that require significant manual corrections. ABACS™ yields highly accurate body composition metrics and substitutes time-consuming manual segmentation with a highly efficient, fully-automated workflow that requires only minimal manual editing.
ABACS™ version 1.0 automatically segments skeletal muscle (SM), subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT) and intramuscular adipose tissue (IMAT) at L3 and T4 axial slices with incredible accuracy.
ABACS is currently available as a module in our Data Analysis Facilitation Suite™.
Abdominal muscle and fat estimation with Jaccard scores over 90%.
Thoracic muscle and subcutaneous fat estimation with Jaccard scores over 90%.
Popuri, K., Cobzas, D., Esfandiari, N., Baracos, V., & Jagersand, M. (2016). Body Composition Assessment in Axial CT Images Using FEM-Based Automatic Segmentation of Skeletal Muscle. IEEE Transactions on Medical Imaging, 35(2), 512-520.
Cespedes Feliciano, E. M., Popuri, K., Cobzas, D., Baracos, V. E., Beg, M. F., Khan, A. D., Ma, C., Chow, V., Prado, C. M., Xiao, J., Liu, V., Chen, W. Y., Meyerhardt, J., Albers, K. B., and Caan, B. J. ( 2020) Evaluation of automated computed tomography segmentation to assess body composition and mortality associations in cancer patients, Journal of Cachexia, Sarcopenia and Muscle,
Williams, G., Deal, A., Muss, H., Weinberg, M., Sanoff, H., Guerard, E., . . . Shachar, S. (2018). Frailty and skeletal muscle in older adults with cancer . Journal of Geriatric Oncology, 9(1), 68-73.
Shachar, S., Deal, A., Weinberg, M., Williams, G., Nyrop, K., Popuri, K., . . . Muss, H. (2017). Body Composition as a Predictor of Toxicity in Patients Receiving Anthracycline and Taxane-Based Chemotherapy for Early-Stage Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(14), 3537-3543.
Shachar, S., Deal, A., Weinberg, M., Nyrop, K., Williams, G., Nishijima, T., . . . Muss, H. (2017). Skeletal Muscle Measures as Predictors of Toxicity, Hospitalization, and Survival in Patients with Metastatic Breast Cancer Receiving Taxane-Based Chemotherapy. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(3), 658-665.
Solheim, T., Laird, B., Balstad, T., Stene, G., Bye, A., Johns, N., . . . Kaasa, S. (2017). A randomized phase II feasibility trial of a multimodal intervention for the management of cachexia in lung and pancreatic cancer. Journal of Cachexia, Sarcopenia and Muscle, 8(5), 778-788.
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